decitabine and cedazuridine (Oral)

Medically reviewed by Drugs.com. Last updated on Jan 17, 2022.

Commonly used brand name(s)

In the U.S.

• Inqovi

Available Dosage Forms:

• Tablet

Therapeutic Class: Antineoplastic Agent

Pharmacologic Class: Antimetabolite

Uses for decitabine and cedazuridine

Decitabine and cedazuridine combination is used to treat myelodysplastic syndromes (MDS), including chronic myelomonocytic leukemia (CMML), and certain types of anemia. Myelodysplastic syndromes are a group of cancers, in which immature blood cells in the bone marrow do not mature and do not become healthy blood cells.

decitabine and cedazuridine is available only with your doctor's prescription.

Before using decitabine and cedazuridine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For decitabine and cedazuridine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to decitabine and cedazuridine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of decitabine and cedazuridine combination in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of decitabine and cedazuridine combination in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking decitabine and cedazuridine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using decitabine and cedazuridine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Azacitidine
• Capecitabine
• Cytarabine
• Cytarabine Liposome
• Gemcitabine

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems

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