Delafloxacin (Intravenous)
Medically reviewed by Drugs.com. Last updated on Jan 13, 2022.
Fluoroquinolones have been associated with disabling and potentially irreversible serious adverse reactions that have occurred together, including tendinitis and tendon rupture, peripheral neuropathy, and central nervous system effects. Discontinue delafloxacin immediately and avoid the use of fluoroquinolones, including delafloxacin, in patients who experience any of these serious adverse reactions. Fluoroquinolones may exacerbate muscle weakness in patients with myasthenia gravis. Avoid delafloxacin in patients with known history of myasthenia gravis .
Commonly used brand name(s)
In the U.S.
- Baxdela
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Antibiotic
Chemical Class: Fluoroquinolone
Uses for delafloxacin
Delafloxacin injection is used to treat acute bacterial skin and skin structure infections (ABSSSI) and community-acquired bacterial pneumonia (CABP).
Delafloxacin belongs to the class of drugs, known as quinolone antibiotics. It works by killing bacteria or preventing their growth. However, delafloxacin will not work for colds, flu, or other virus infections.
Delafloxacin is to be given only by or under the direct supervision of your doctor.
Before using delafloxacin
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For delafloxacin, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to delafloxacin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Use in children is not recommended. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of delafloxacin injection in the elderly. However, elderly patients are more likely to have age-related kidney problems, or develop aortic aneurysm or severe tendon disorders (including tendon rupture), especially in those who also take steroid medicines, which may require caution in patients receiving delafloxacin injection.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving delafloxacin, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
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