Delos Lotion
Generic name:benzoyl peroxide
Dosage form: lotion
Drug class:Topical acne agents
Medically reviewed by Drugs.com. Last updated on Mar 22, 2022.
Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.
On This Page
Delos Lotion Description
Delos™ (3.5% benzoyl peroxide) lotion is a topical preparation containing benzoyl peroxide, for use in the treatment of acne vulgaris, and patented Novasome encapsulation technology to help provide continuous hydration and moisturization to minimize the appearance of skin dryness. Benzoyl peroxide is an oxidizing agent that possesses antibacterial properties and is classified as a keratolytic agent. Benzoyl peroxide (C14H O4) is represented by the following chemical structure:
Delos™ (3.5% benzoyl peroxide) lotion contains benzoyl peroxide USP 3.5% as the active ingredient in a formulation consisting of: Allantoin, Aloe Barbadensis Leaf Juice, Butylene Glycol, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Cetearyl Glucoside, Cetearyl Olivate, Cetyl Alcohol, Dimethicone, Edetate Disodium, Ethylene/Acrylic Acid Copolymer, Glycerin, Glycine Soya (Soybean) Sterols, Methylparaben, Phenoxyethanol, Propylparaben, Purified Water, Sorbitan Olivate, Stearyl Alcohol, Tocopheryl Acetate, and Xanthan Gum.
Delos Lotion - Clinical Pharmacology
The mechanism of action of benzoyl peroxide is not totally understood but its antibacterial activity against Propionibacterium acnes is thought to be a major mode of action, in addition, patients treated with benzoyl peroxide show a reduction in lipids and free fatty acids, and mild desquamation (drying and peeling activity) with simultaneous reduction in comedones and acne lesions. Little is known about the percutaneous penetration, metabolism, and excretion of benzoyl peroxide, although it has been shown that benzoyl peroxide absorbed by the skin is metabolized to benzoic acid and then excreted as benzoate in the urine. There is no evidence of systemic toxicity caused by benzoyl peroxide in humans.
