Desonide

Dosage form: ointment
Drug class:Topical steroids

Medically reviewed by Drugs.com. Last updated on Nov 1, 2021.

For Dermatologic Use Only. Not for Ophthalmic Use.

Rx Only

Desonide Description

Desonide ointment, 0.05% contains Desonide (Pregna-1,4-diene-3,20-dione,11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-,(11β,16α)) a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primary synthetic steroids used topically as anti-inflammatory and antipruritic agents.

Chemically, Desonide, the active ingredient in Desonide ointment, 0.05% is C24H32O6. It has the following structural formula:

The molecular weight of Desonide is 416.51. It is white to off-white powder. The solubility of Desonide in distilled water saturated with the ether is 184 mg/L.

Each gram of Desonide ointment, 0.05% contains 0.5 mg of Desonide microdispersed in a base of white petrolatum.

Desonide - Clinical Pharmacology

Like other topical corticosteroids, Desonide has anti-inflammatory, antipruritic, and vasoconstrictive properties. The mechanism of the anti-inflammatory activity of the topical steroids, in g...