Deutetrabenazine
Generic name: deutetrabenazine [ doo-TET-ra-BEN-a-zeen ]
Brand name: Austedo
Dosage form: oral tablet (12 mg; 6 mg; 9 mg)
Drug class:VMAT2 inhibitors
What is deutetrabenazine?
Deutetrabenazine is used to treat involuntary muscle movements (chorea) caused by Huntington's disease. Deutetrabenazine is not a cure for Huntington's disease and will not treat other symptoms of this condition.
Deutetrabenazine is used to treat symptoms of tardive dyskinesia, a nervous system disorder. Tardive dyskinesia causes repetitive uncontrolled muscle movements, usually in the face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement).
Deutetrabenazine is not a permanent cure for involuntary movement disorders.
Deutetrabenazine may also be used for purposes not listed in this medication guide.
Warnings
You should not use deutetrabenazine if you have liver disease, untreated or uncontrolled depression, or if you have thoughts about suicide.
Do not use deutetrabenazine if you have taken reserpine (Serpalan, Renese-R) in the past 20 days, or if you have used an MAO inhibitor (isocarboxazid, linezolid, rasagiline, selegiline, and others) in the past 14 days.
Stay alert to changes in your mood, feelings, thoughts, or behaviors. Report any new or worsening symptoms to your doctor.
Before taking this medicine
You should not use deutetrabenazine if you are allergic to it, or if you have:
untreated or uncontrolled depression;
thoughts about suicide or hurting yourself;
liver disease; or
if you have recently taken tetrabenazine (Xenazine) or valbenazine (Ingrezza).
Do not use deutetrabenazine if you have taken reserpine (Serpalan, Renese-R) in the past 20 days, or if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
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