Dextran 70 6% in 5% Dextrose (high molecular weight)

Generic name:dextran (high molecular weight) [ DEX-tran ]
Brand names: Dextran 70 6% in 5% Dextrose, Hyskon
Drug class:Plasma expanders

Medically reviewed by Drugs.com on Nov 16, 2021. Written by Cerner Multum.

What is high-molecular weight Dextran 70 6% in 5% Dextrose?

High-molecular weight Dextran 70 6% in 5% Dextrose is a plasma volume expander made from natural sources of sugar (glucose). It works by restoring blood plasma lost through severe bleeding. Severe blood loss can decrease oxygen levels and can lead to organ failure, brain damage, coma, and possibly death. Plasma is needed to circulate red blood cells that deliver oxygen throughout the body.

Dextran 70 6% in 5% Dextrose is used to treat hypovolemia (decreased volume of circulating blood plasma), that can result from surgery, trauma or injury, severe burns, or other causes of bleeding.

Dextran 70 6% in 5% Dextrose may also be used for purposes not listed in this medication guide.

Warnings

You should not receive this medication if you have severe kidney disease, severe congestive heart failure, or uncontrolled bleeding.

Before taking this medicine

You should not receive this medication if you are allergic to Dextran 70 6% in 5% Dextrose, or if you have

• severe kidney disease

• severe congestive heart failure; or

• uncontrolled bleeding.

If possible before you receive Dextran 70 6% in 5% Dextrose 70 6% in 5% Dextrose, tell your doctor if you have:

• liver or kidney disease;

• a bleeding or blood clotting disorder such as hemophilia or thrombocytopenic purpura (easy bruising or bleeding);

• heart disease, fluid retention;

• asthma or breathing problems;

• diabetes;

• epilepsy, seizures, or migraine headaches;

• a stomach or intestinal disorder;

• a food or drug allergy; or

• if you are on a low-salt diet.

In an emergency situation it may not be possible to tell your caregivers about your health conditions. Make sure any doctor caring for you afterward knows you have received this medicine.

FDA pregnancy category C. It is not known whether high-molecular weight Dextran 70 6% in 5% Dextrose will harm an unborn baby. Tell your doctor if you are pregnant.

It is not known whether high-molecular weight dextran passes into breast milk or if it could harm a ...