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Dextromethorphan and promethazine
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Dextromethorphan and promethazine

Generic name: dextromethorphan and promethazine [ dex-troe-me-THOR-fan-and-pro-METH-a-zeen ]
Brand names: Promethazine DM, Phenergan with Dextromethorphan, Promethazine with DM, Promethazine with Dextromethorphan
Dosage form: oral syrup (15 mg-6.25 mg/5 mL)
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com on Jul 1, 2021. Written by Cerner Multum.

What is dextromethorphan and promethazine?

Dextromethorphan is a cough suppressant. Promethazine is an antihistamine.

Dextromethorphan and promethazine is a combination medicine used to treat cough, stuffy nose, runny nose, and sneezing caused by colds or allergies.

dextromethorphan and promethazine is for use in adults and children at least 2 years old.

Dextromethorphan and promethazine may also be used for purposes not listed in this medication guide.

Warnings

Promethazine can slow the breathing, which has caused death in very young children. Do not use this medicine in a child younger than 2 years old. Follow all directions when giving the medicine to a child 2 years or older.

Do not use dextromethorphan and promethazine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Before taking this medicine

You should not use dextromethorphan and promethazine if you are allergic to dextromethorphan or promethazine, or if you have:

Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.

Tell your doctor if you have ever had: