Dextromethorphan and quinidine
Generic name: dextromethorphan and quinidine [ DEX-troe-me-THOR-fan-and-KWIN-i-deen ]
Brand name: Nuedexta
Dosage form: oral capsule (20 mg-10 mg)
Drug class:Miscellaneous central nervous system agents
What is dextromethorphan and quinidine?
Dextromethorphan and quinidine is a combination medicine used to treat involuntary outbursts of crying or laughing in people with certain neurological disorders, including multiple sclerosis and amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease).
Dextromethorphan and quinidine may also be used for purposes not listed in this medication guide.
Warnings
You should not use dextromethorphan and quinidine if you have heart failure, a serious heart condition called "AV block" (unless you have a pacemaker), or a life-threatening heart rhythm disorder.
You also should not take dextromethorphan and quinidine if you are also taking mefloquine, quinidine, or quinine, or if you have ever had an allergic reaction or serious medical problem caused by taking any of these medications.
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
Before taking this medicine
You should not take this medicine if you are allergic to dextromethorphan or quinidine, or if you have:
heart failure;
a history of life-threatening heart rhythm disorder;
long QT syndrome (in you or a family member);
a serious heart condition called "AV block" (unless you have a pacemaker); or
if you also use mefloquine, quinidine, or quinine.
You also should not take dextromethorphan and quinidine if you have ever had any of the following problems caused by taking mefloquine, quinidine, or quinine:
bruising or bleeding;
hepatitis;
an allergic reaction; or
lupus-like symptoms (joint pain, fever, skin rash on your cheeks).
Do not use dextromethorphan and quinidine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include
