Dextromethorphan, diphenhydramine, and phenylephrine

Generic name: dextromethorphan, diphenhydramine, and phenylephrine [ DEX-troe-me-THOR-fan, DYE-fen-HYE-dra-meen, and-FEN-il-EFF-rin ]
Brand names: Dytan-DM, Triaminic Day Time Night Time Cold & Cough, Duratuss AC 12, D-Tann DM, Triaminic Day Time Night Time Cold and Cough
Dosage forms: oral liquid (varying strength); oral suspension, extended release (75 mg-25 mg-7.5 mg/5 mL)
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com on Sep 29, 2020. Written by Cerner Multum.

What is dextromethorphan, diphenhydramine, and phenylephrine?

Dextromethorphan is a cough suppressant. Diphenhydramine is an antihistamine. Phenylephrine is a decongestant.

Dextromethorphan, diphenhydramine, and phenylephrine is a combination medicine used to treat cough, stuffy nose, and sneezing caused by allergies, the common cold, or the flu.

dextromethorphan, diphenhydramine, and phenylephrine will not treat a cough that is caused by smoking, asthma, or emphysema.

Dextromethorphan, diphenhydramine, and phenylephrine may also be used for purposes not listed in this medication guide.

Warnings

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Use this medicine exactly as directed. Taking too much diphenhydramine can lead to serious heart problems, seizures, coma, or death.

Do not use this medicine to make a child sleepy. Ask a doctor before giving the medicine to a child younger than 4 years old.

Ask a doctor or pharmacist before using any other medicine that may contain diphenhydramine. Taking too much of this medicine can lead to a fatal overdose.

Before taking this medicine

Do not use this medicine if you have used an ...