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Dienogest and estradiol
  • Treatments
  • Birth Control

Dienogest and estradiol

Generic name: dienogest and estradiol [ dye-EN-oh-jest-and-ESS-tra-DYE-ole ]
Brand name: Natazia
Dosage form: oral tablet (multiphasic)
Drug class:Contraceptives

Medically reviewed by Drugs.com on Jan 25, 2022. Written by Cerner Multum.

What is dienogest and estradiol?

Dienogest and estradiol is a combination drug that contains female hormones that prevent ovulation (the release of an egg from an ovary). dienogest and estradiol also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Dienogest and estradiol is used to prevent pregnancy. This medicine is also used to treat heavy menstrual bleeding that is not caused by any medical condition of the uterus.

Dienogest and estradiol may also be used for purposes not listed in this medication guide.

Warnings

Do not use this medicine if you are pregnant or if you have recently had a baby.

You should not take this medicine if you have any of the following conditions: uncontrolled high blood pressure, heart disease, a blood-clotting disorder, circulation problems, diabetic problems with your eyes or kidneys, unusual vaginal bleeding, liver disease or liver cancer, severe migraine headaches, if you smoke and are over 35, or if you have ever had breast or uterine cancer, a heart attack, a stroke, or a blood clot.

Taking this medicine can increase your risk of blood clots, stroke, or heart attack, especially if you have certain other conditions, or if you are overweight.

Smoking can greatly increase your risk of blood clots, stroke, or heart attack. You should not take dienogest and estradiol if you smoke and are over 35 years old.

Missing a pill increases your risk of becoming pregnant. Carefully follow the "missed dose" instructions if you forget to take your medicine.

Before taking this medicine

Taking dienogest and estradiol can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, or if you are overweight. Your risk of stroke or blood clot is highest during your first year of taking dienogest and estradiol. Your risk is also high when you restart this medicine after not taking it for 4 weeks or long...