Dihydrocodeine, Aspirin and Caffeine
Generic name: dihydrocodeine bitartrate, aspirin and caffeine
Dosage form: capsule
Drug class:Narcotic analgesic combinations
Medically reviewed by Drugs.com. Last updated on Apr 21, 2022.
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WARNING: DEATH RELATED TO ULTRA-RAPID METABOLISM OF CODEINE TO MORPHINE
Respiratory depression and death have occurred in children who received codeine following tonsillectomy and/or adenoidectomy and had evidence of being ultra-rapid metabolizers of codeine due to a CYP2D6 polymorphism.
Dihydrocodeine, Aspirin and Caffeine Description
Each Aspirin, Caffeine, and Dihydrocodeine Bitartrate Capsule, USP contains 356.4 mg aspirin, 30 mg caffeine, and 16 mg drocode (dihydrocodeine) bitartrate (Warning–may be habitforming).
The inactive ingredients present are alginic acid, cellulose, D&C Red 28, FD&C Blue 1, gelatin, iron oxides, stearic acid, and titanium dioxide.
Dihydrocodeine, Aspirin and Caffeine - Clinical Pharmacology
Dihydrocodeine is a semisynthetic narcotic analgesic, related to codeine, with multiple actions qualitatively similar to those of codeine; the most prominent of these involve the central nervous system and organs with smooth-muscle components. The principal action of therapeutic value is analgesia.
Aspirin, Caffeine, and Dihydrocodeine Bitartrate Capsule, USP also contains the nonnarcotic antipyretic-analgesic, aspirin.
Indications and Usage for Dihydrocodeine, Aspirin and Caffeine
For the relief of moderate to moderately severe pain.
Contraindications
Aspirin, Caffeine, and Dihydrocodeine Bitartrate Capsule, USP is contraindicated for postoperative pain management in children who have undergone tonsillectomy and/or adenoidectomy.
Aspirin, Caffeine, and Dihydrocodeine Bitartrate Capsule, USP is contraindicated in patients with hypersensitivity to dihydrocodeine, codeine, or aspirin.
Warnings
Salicylates should be used with extreme caution in the presence of peptic ulcer or coagulation abnormalities.
