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Dilex-G 400 Tablets
  • Professionals
  • FDA PI

Dilex-G 400 Tablets

Generic name:guaifenesin and dyphylline
Dosage form: tablet
Drug class:Antiasthmatic combinations

Medically reviewed by Drugs.com. Last updated on Mar 22, 2022.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

DOSAGE AND ADMINISTRATION:DO NOT EXCEED RECOMMENDED DOSAGE. The usual adult dose is 1 tablet taken orally 3 or 4 times daily. In severe cases, dosage may be doubled or tripled if necessary. Maintenance dosage should be adjusted according to patient response.

Dyphylline is s bronchodilator which occurs as a white, odorless, extremely bitter, amorphous crystalline solid. It is freely soluble in water; sparingly soluble in alcohol and in chloroform; practically insoluble in ether. The chemical name is 1H-Purine-2, 6-dione, 7-(2, 3 dihydroxypropyl)-3-7dihydro-1, 3-dimethyl. It's chemical structure is as follows:



C10H14N4O4 M.W. 254.25




Guaifenesin is an expectorant which occurs as a white to slightly gray, crystalline powder, having a bitter taste. It may have a slight characteristic odor. It is soluble in water, alcohol, chloroform, glycerin, and propylene glycol. The chemical name is 1, 2-Propanediol, 3-(2-methoxyphenoxy). Its structural formula is as follows:

C10H14O4 M.W. 198.22

CLINICAL PHARMACOLOGY

Dyphylline is a xanthine derivative with pharmacological actions similar to those of theophylline and other members of this class of drug. Its primary action is that of bronchodilation, but it also exhibits peripheral vasodilatory and other smooth muscle relaxant activity to a lesser d.