Aklief Cream
Generic name:trifarotene
Dosage form: cream
Drug class:Topical acne agents
Medically reviewed by Drugs.com. Last updated on Apr 21, 2022.
On This Page
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Clinical Studies
- Drug Interactions
- Use In Specific Populations
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- How Supplied/Storage and Handling
- Patient Counseling Information
Indications and Usage for Aklief Cream
Aklief Cream is a retinoid indicated for the topical treatment of acne vulgaris in patients 9 years of age and older.
Aklief Cream Dosage and Administration
Apply a thin layer of Aklief Cream to the affected areas once daily, in the evening, on clean and dry skin.
- One pump actuation should be enough to cover the face (i.e., forehead, cheeks, nose, and chin).
- Two actuations of the pump should be enough to cover the upper trunk (i.e., reachable upper back, shoulders and chest). One additional pump actuation may be used for middle and lower back if acne is present.
The use of a moisturizer is recommended as frequently as needed from the initiation of treatment.
Avoid contact with the eyes, lips, paranasal creases, mucous membranes.
Aklief Cream is for topical use only. Not for oral, ophthalmic, or intravaginal use.
Dosage Forms and Strengths
Cream: 0.005%. Each gram of Aklief Cream contains 50 mcg of trifarotene in a white cream.
Contraindications
None
Warnings and Precautions
Skin Irritation
Patients using Aklief Cream may experience erythema, scaling, dryness, and stinging/burning. Maximum severity of these reactions typically occurred within the first 4 weeks of treatment, and severity decreased with continued use of the medication. Depending upon the severity of these adverse reactions, instruct patients to use a moisturizer, reduce the frequency of application of Aklief Cream, or suspend use temporarily. If severe reactions persist the treatment may be discontinued.
Avoid applic