Dimethyl fumarate
Generic name: dimethyl fumarate [ dye-METH-il-FUE-mar-ate ]
Brand names: Tecfidera, Tecfidera Starter Pack
Dosage form: oral delayed release capsule (-; 120 mg; 240 mg)
Drug class:Selective immunosuppressants
What is dimethyl fumarate?
Dimethyl fumarate is used to treat relapsing forms of multiple sclerosis in adults (including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease).
Dimethyl fumarate may also be used for purposes not listed in this medication guide.
Warnings
Dimethyl fumarate may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement. These symptoms may start gradually and get worse quickly.
Before taking this medicine
You should not use dimethyl fumarate if you have had a severe allergic reaction to dimethyl fumarate or diroximel fumarate (Vumerity).
Tell your doctor if you have ever had:
an active infection; or
low white blood cell (WBC) counts.
Tell your doctor if you are pregnant or breastfeeding.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of dimethyl fumarate on the baby.
Dimethyl fumarate is not approved for use by anyone younger than 18 years old.
How should I take dimethyl fumarate?
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using dimethyl fumarate.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may take dimethyl fumarate with or without food. Taking the medicine with food may help prevent flushing (sudden warmth, redness, or tingly feeling).
Swallow the capsule whole and do not crush, chew, break, or open it.
While using dimethyl fumarate, you will need frequent blood tests.
Store this medicine in the original container at room temperature, away from moisture, heat, and light.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking dimethyl fumarate?
Follow your doctor's instructions about any restrictions on food, be...
