Dinutuximab
Generic name: dinutuximab [ DIN-ue-TUX-i-mab ]
Brand name: Unituxin
Dosage form: intravenous solution (17.5 mg/5 mL)
Drug class:Miscellaneous antineoplastics
What is dinutuximab?
Dinutuximab is used with other medicines to treat neuroblastoma (a rare cancer of the nervous system) in children.
Dinutuximab is usually given after the child has had some improvement from other treatments.
Dinutuximab may also be used for purposes not listed in this medication guide.
Warnings
Call your doctor at once if your child has severe or worsening pain, numbness, tingling, weakness, or problems with walking or daily activities.
Some side effects may occur during the injection or up to 24 hours afterward, including dizziness, skin rash, chest tightness, wheezing, trouble breathing, or swelling in the face.
Before taking this medicine
Your child should not be treated with dinutuximab if you are allergic to it.
Tell your doctor if the child has ever had:
any type of bacterial, fungal, or viral infection;
an eye disorder or vision problems;
bone marrow suppression;
an electrolyte imbalance (such as low blood levels of potassium, sodium, or calcium);
liver or kidney disease; or
urination problems.
How is dinutuximab given?
Dinutuximab is injected into a vein.
dinutuximab is injected slowly over 10 to 20 hours.
Dinutuximab is given in a 28-day treatment cycle. Your child will receive this injection only on certain days of the cycle.
Your doctor will decide how many cycles your child should receive.
Your child may be given other medicines to help prevent certain side effects.
Your child will be watched for at least 4 hours to make sure he or she does not have a reaction to the medicine.
Your child may need frequent medical tests and treatment may be delayed based on the results.
What happens if I miss a dose?
In a medical setting your child is not likely to miss a dose.
What happens if I overdose?
In a medical setting an overdose would be treated quickly.
What should I avoid after receiving dinutuximab?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Dinutuximab side effects
Get emergency medical help if your child has signs of an allergic reacti...
