Akynzeo
Generic name:netupitant and palonosetron (oral) [ net-UE-pi-tant-and-PAL-oh-NOE-se-tron ]
Drug class:Miscellaneous antiemetics
What is Akynzeo?
Akynzeo contains a combination of netupitant and palonosetron.
Akynzeo is used to help prevent nausea and vomiting caused by chemotherapy. This medicine is given together with a steroid called dexamethasone.
Akynzeo helps prevent nausea and vomiting that occurs both during chemotherapy and later on (delayed nausea and vomiting).
Warnings
Before you take Akynzeo, tell your doctor if you are pregnant or plan to become pregnant. Netupitant and palonosetron may harm your unborn baby. Tell your doctor if you are breastfeeding or plan to breastfeed. You and your doctor should decide if you will take Akynzeo or breastfeed. You should not do both.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
Akynzeo is not approved for use by anyone younger than 18 years old.
To make sure this medicine is safe for you, tell your doctor if you have ever had:
liver or kidney disease; or
an allergic reaction to a medicine for nausea or vomiting, such as dolasetron (Anzemet), ondansetron (Zofran), or palonosetron (Aloxi).
Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, or serious infections. These medicines may interact with netupitant and palonosetron and cause a serious condition called serotonin syndrome.
Netupitant and palonosetron may harm an unborn baby. Tell your doctor if you become pregnant.
You should not breast-feed while using this medicine.
How should I take Akynzeo?
Take Akynzeo exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Akynzeo is given ahead of time and will not treat nausea or vomiting you already have.
About 1 hour before chemotherapy, you will take Akynzeo with or without food.
You will take dexamethasone 30 minutes before chemotherapy, and you may need to kee...
