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Dormosedan
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  • FDA PI

Dormosedan

Generic name: detomidine hydrochloride oromucosal gel
Dosage form: FOR ANIMAL USE ONLY

Rx only

For Sedation and Restraint in Horses Only

CAUTION

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Dormosedan Description

Dormosedan (detomidine hydrochloride) GEL is a synthetic alpha2-adrenoreceptor agonist with sedative properties. Each mL of Dormosedan GEL contains 7.6 mg detomidine hydrochloride. The chemical name is 1H imidazole, 4-[(2,3-dimethylphenyl) methyl]-hydrochloride. Detomidine hydrochloride is a white, crystalline, water-soluble substance having a molecular weight of 222.7. The molecular formula is C12H14N2•HCl and the structural formula is

INDICATIONS

Dormosedan GEL is indicated for sedation and restraint in horses.

Dormosedan Dosage and Administration

Dormosedan GEL produces sedation when administered sublingually at 0.018 mg/lb (0.040 mg/kg). Dormosedan GEL must be placed beneath the tongue of the horse and is not meant to be swallowed. The dosing syringe delivers the product in 0.25 mL increments. The following dosing table may be used to determine the correct dose of Dormosedan GEL (Table 1).

Table 1: Sublingual dosing of Dormosedan GEL
Approximate body weight (lb)Range of doses (mg/lb)Approximate body weight (kg)Range of doses (mg/kg)Dose volume (mL)
330 - 4390.023 – 0.017150 - 1990.051 – 0.038
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