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Dostarlimab
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Dostarlimab

Generic name: dostarlimab [ dos-TAR-li-mab ]
Brand name: Jemperli
Dosage form: intravenous solution (500 mg/10 mL)
Drug class:Anti-PD-1 monoclonal antibodies

Medically reviewed by Drugs.com on May 26, 2021. Written by Cerner Multum.

What is dostarlimab?

Dostarlimab is used to treat a certain type of uterine cancer after other treatments did not work or stopped working.

Your doctor will make sure you have the correct tumor type to be treated with dostarlimab.

Dostarlimab may also be used for purposes not listed in this medication guide.

Warnings

Call your doctor at once if you have new or worsening symptoms such as: cough, chest pain, breathing problems, severe stomach pain, diarrhea, bloody or tarry stools, headaches, confusion, severe weakness, vision problems, decreased urination, bruising or bleeding, blood in your urine, dark urine, or yellowing of the skin or eyes.

Before taking this medicine

Tell your doctor if you have ever had:

  • breathing problems; or

  • immune system problems.

May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use birth control while using dostarlimab and for at least 4 months after your last dose. Tell your doctor if you become pregnant.

Do not breastfeed while using dostarlimab, and for at least 4 months after your last dose.

How is dostarlimab given?

Dostarlimab is injected into a vein by a healthcare provider. This medicine is injected slowly over 30 minutes.

Dostarlimab is usually given every 3 weeks at first, and then every 6 weeks.

You may need medical tests to help determine how long you should use dostarlimab.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your dostarlimab injection.

What happens if I overdose?

Since dostarlimab is given in a medical setting, an overdose is unlikely.

What should I avoid while receiving dostarlimab?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Dostarlimab side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Some side effects may o...