Dostarlimab-gxly (Intravenous)

Medically reviewed by Drugs.com. Last updated on Apr 26, 2022.

Commonly used brand name(s)

In the U.S.

Jemperli

Available Dosage Forms:

Solution

Therapeutic Class: Antineoplastic Agent

Pharmacologic Class: Dostarlimab

Uses for dostarlimab-gxly

Dostarlimab-gxly injection is used to treat endometrial cancer (cancer of the lining of the uterus or womb) that is mismatch repair deficient (dMMR) in patients whose cancer has returned, or it has spread or cannot be removed by surgery. It is given to patients who have received other cancer medicines (eg, platinum) that did not work well. Your doctor will perform a test to check for the dMMR tumor before you use dostarlimab-gxly.

Dostarlimab-gxly is a monoclonal antibody that changes the immune system to help control the growth of cancer cells.

Dostarlimab-gxly is to be given only by or under the direct supervision of your doctor.

Before using dostarlimab-gxly

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For dostarlimab-gxly, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to dostarlimab-gxly or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of dostarlimab-gxly injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of dostarlimab-gxly injection in the elderly.

Breastfeeding

Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using dostarlimab-gxly.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Dostarlimab-gxly Intravenous