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Doxylamine and phenylephrine
  • Treatments
  • Cold Symptoms

Doxylamine and phenylephrine

Generic name: doxylamine and phenylephrine [ dox-IL-a-meen-and-FEN-il-EFF-rin ]
Brand name: Poly Hist Forte
Dosage form: oral tablet (10.5 mg-10 mg; 7.5 mg-10 mg)
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com on Jun 18, 2021. Written by Cerner Multum.

What is doxylamine and phenylephrine?

Doxylamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Doxylamine and phenylephrine is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu.

Doxylamine and phenylephrine may also be used for purposes not listed in this medication guide.

Warnings

Do not use doxylamine and phenylephrine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Do not use this medicine only to make a child sleepy.

Before taking this medicine

You should not use this medicine if you are allergic to doxylamine or phenylephrine.

Do not use doxylamine and phenylephrine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Ask a doctor or pharmacist if this medicine is safe to use if you have: