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Drospirenone and estetrol
  • Treatments
  • Birth Control

Drospirenone and estetrol

Generic name: drospirenone and estetrol [ droe-SPYE-re-none-and-ES-te-trol ]
Brand name: Nextstellis
Dosage form: oral tablet (3 mg-14.2 mg)
Drug class:Contraceptives

Medically reviewed by Drugs.com on Jun 17, 2021. Written by Cerner Multum.

What is drospirenone and estetrol?

Drospirenone and estetrol is a combination hormonal birth control that is used to prevent pregnancy.

Drospirenone and estetrol may also be used for purposes not listed in this medication guide.

Warnings

Smoking can greatly increase your risk of blood clots, stroke, or heart attack. You should not use drospirenone and estetrol if you smoke and are older than 35 years of age.

Before taking this medicine

Using hormonal birth control can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you have high blood pressure, diabetes, high cholesterol, or if you are overweight. Your risk of stroke or blood clot is highest during your first year of using birth control. Your risk is also high when you restart this medicine after not using for 4 weeks or longer.

Smoking can greatly increase your risk of blood clots, stroke, or heart attack. Your risk increases the older you are and the more you smoke. You should not use this medicine if you smoke and are over 35 years old.

You should not use hormonal birth control if you have:

  • untreated or uncontrolled high blood pressure;

  • high blood pressure with blood vessel problems;

  • heart problems (heart valve disorder or heart rhythm disorder);

  • a history of heart attack, stroke, or blood clot;

  • an increased risk of having blood clots due to a hereditary blood disorder;

  • diabetes (and you've had diabetes longer than 20 years, or if diabetes has caused damage to your kidneys, eyes, nerves, or blood vessels);

  • a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina;

  • unusual vaginal bleeding that has not been checked by a doctor;

  • adrenal gland problems;

  • liver disease or liver cancer;

  • kidney disease or kidney failure;

  • severe migraine headaches with aura;

  • if...