Dtic-Dome
Generic name:dacarbazine (intravenous route, injection route) [ da-KAR-ba-zeen ]
Drug class:Alkylating agents
Medically reviewed by Drugs.com. Last updated on Jan 30, 2022.
Hemopoietic depression is the most common toxicity with dacarbazine for injection. Hepatic necrosis has also been reported. Studies have demonstrated this agent to have a carcinogenic and teratogenic effect when used in animals .
The DTIC-Dome brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Commonly used brand name(s)
In the U.S.
- Dtic-Dome
In Canada
- Dacarbazine
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Antineoplastic Agent
Pharmacologic Class: Alkylating Agent
Chemical Class: Imidazole Carboxamide
Uses for Dtic-Dome
Dacarbazine belongs to the group of medicines called alkylating agents. It is used to treat cancer of the lymph system and malignant melanoma (a type of skin cancer). It may also be used to treat other kinds of cancer, as determined by your doctor.
Dacarbazine interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by dacarbazine, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.
Before you begin treatment with dacarbazine, you and your doctor should talk about the good this medicine will do as well as the risks of using it.
Dacarbazine is to be administered only by or under the immediate supervision of your doctor.
Before using Dtic-Dome
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Studies on this medicine have been done only in adult patients and there is no specific information comparing use of dacarbazine in children with use in other age groups.
Geriatric
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information about the use of dacarbazine in the elderly.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication..
