Generic name:famotidine and ibuprofen [ fam-OH-ti-deen-and-EYE-bue-PROE-fen ]
Drug class:Nonsteroidal anti-inflammatory drugs
What is Duexis?
Duexis contains a combination of famotidine and ibuprofen. Famotidine is a histamine blocker. Famotidine works by decreasing the amount of acid the stomach produces.
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen works by reducing hormones that cause inflammation and pain in the body.
Duexis is a combination drug. Ibuprofen treats the symptoms of arthritis. Famotidine helps reduce the risk of ulcers in the stomach or intestines that can be caused by long-term use of ibuprofen.
Taking famotidine (Pepcid) and ibuprofen (Advil, Motrin) together does not have the same effect as using Duexis.
Warnings
Ibuprofen can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Do not use Duexis just before or after heart bypass surgery (coronary artery bypass graft, or CABG).
Ibuprofen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using Duexis, especially in older adults.
Before taking this medicine
You should not use Duexis if you are allergic to famotidine or ibuprofen, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.
Ibuprofen can increase your risk of fatal heart a...
