Medically reviewed by Drugs.com. Last updated on Apr 16, 2022.
In male and female rats, dulaglutide caused a dose-related and treatment-duration-dependent increase in the incidence of thyroid C-cell tumors (adenomas and carcinomas) after lifetime exposure. It is unknown whether dulaglutide causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans as human relevance of dulaglutide-induced rodent thyroid C-cell tumors has not been determined. Dulaglutide is contraindicated in patients with a personal or family history of MTC and in patients with multiple endocrine neoplasia syndrome type 2 (MEN 2). Counsel patients regarding the potential risk of MTC with use of dulaglutide and inform them of symptoms of thyroid tumors (eg, mass in the neck, dysphagia, dyspnea, persistent hoarseness). Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with dulaglutide .
Commonly used brand name(s)
In the U.S.
- Trulicity
Available Dosage Forms:
- Solution
Therapeutic Class: Antidiabetic
Pharmacologic Class: Glucagon-Like Peptide-1 Receptor Agonist
Uses for dulaglutide
Dulaglutide injection is used to treat type 2 diabetes mellitus. Dulaglutide is used together with diet and exercise to help control your blood sugar. Dulaglutide also lowers the risk of death, heart attack, or stroke in patients with diabetes and heart or blood vessel problems.
Dulaglutide is available only with your doctor's prescription.
Before using dulaglutide
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For dulaglutide, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to dulaglutide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
