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Duvelisib
  • Treatments
  • Chronic Lymphocytic Leukemia

Duvelisib

Generic name: duvelisib [ DOO-ve-LIS-ib ]
Brand name: Copiktra
Dosage form: oral capsule (15 mg; 25 mg)
Drug class:PI3K inhibitors

Medically reviewed by Drugs.com on Oct 5, 2021. Written by Cerner Multum.

What is duvelisib?

Duvelisib is used to treat adults with chronic lymphocytic leukemia or small lymphocytic leukemia. Duvelisib is also used to treat follicular lymphoma.

Duvelisib is given after at least two other cancer treatments did not work or have stopped working.

Duvelisib may also be used for purposes not listed in this medication guide.

Warnings

Duvelisib can cause serious or fatal side effects, including serious infections, severe diarrhea, or a life-threatening skin rash.

Call your doctor right away if you have symptoms such as:

  • fever, chills, cough, breathing problems;

  • severe stomach pain, diarrhea with blood or mucus; o

  • painful mouth sores, or a skin rash with blistering or peeling.

Before taking this medicine

Tell your doctor if you have ever had:

Both men and women using duvelisib should use effective birth control to prevent pregnancy. Duvelisib can harm an unborn baby or cause birth defects if the mother or father is using this medicine.

Keep using birth control for at least 1 month after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using duvelisib.

It is not safe to breast-feed a baby while you are using this medicine. Also do not breast-feed for at least 1 month after your last dose.

How should I take duvelisib?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

You may take duvelisib with or without food.

Swallow the capsule whole and do not crush, chew, break, or open it.

Duvelisib can cause severe diarrhea, which can be life-threatening. You may need to take medication to prevent or quickly treat diarrhea.

You may be given other medications to help prevent serious side effects. Keep using these medicines for as long as your doctor has prescribed.

Your doctor will need to check your progress on a regular basis, and you will need frequent medical tests. Your cance...