Dyclopro Topical Solution

Generic name:dyclonine hydrochloride
Dosage form: topical solution
Drug classes:Mouth and throat products, Topical anesthetics

Medically reviewed by Drugs.com. Last updated on Jan 1, 2022.

Description:

DycloPro (Dyclonine Hydrochloride Topical Solution, USP, 0.5% and 1%) topical anesthetics contain a local anesthetic agent and are administered topically. See INDICATIONS for specific uses.

DycloPro (Dyclonine Hydrochloride Topical Solution, USP, 0.5% and 1%) contain dyclonine HCl, which is chemically designated as 4’-butoxy-3-piperidinopropiophenone HCl. Dyclonine HCl is a white crystalline powder that is sparingly soluble in water and has the following structural formula:

COMPOSITION OF Dyclonine HCl Topical Solution, USP, 0.5% and 1% topical anesthetics:

Each mL of Dyclonine HCl Topical Solution, USP, 0.5% contains dyclonine HCl, 5 mg.
Each mL of Dyclonine HCl Topical Solution, USP, 1% contains dyclonine HCl, 10 mg.
Both solutions also contain chlorbutanol hydrous and sodium chloride, and the pH is adjusted 3.0-5.0 by means of hydrochloric acid.

CLINICAL PHARMACOLOGY:

Dyclonine HCl Topical Solution, USP effects surface anesthesia when applied topically to mucous membranes. Effective anesthesia varies with different patients, but usually occurs from 2 to 10 minutes after application and persists for approximately 30 minutes.

INDICATIONS AND USAGE:

Dyclonine HCl Topical Solution, USP is indicated for anesthetizing accessible mucous membranes (e.g., the mouth, pharynx, larynx, trachea, esophagus, and urethra) prior to various endoscopic procedures.

Dyclonine HCl Topical Solution, USP, 0.5% topical anesthetic may also be used to block the gag reflex, to relieve the pain of oral ulcers or stomatitis and to relieve pain associated wi.