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Edaravone
  • Treatments
  • Amyotrophic Lateral Sclerosis

Edaravone

Generic name: edaravone [ e-DAR-a-vone ]
Brand name: Radicava
Dosage form: intravenous solution (30 mg/100 mL)
Drug class:Miscellaneous central nervous system agents

Medically reviewed by Drugs.com on Jun 30, 2021. Written by Cerner Multum.

What is edaravone?

Edaravone works by relieving the effects of oxidative stress, which may be related to the death of motor neurons (nerve cells) in people with Amyotrophic Lateral Sclerosis (ALS). Keeping motor neurons healthy may help to preserve muscle function.

Edaravone is used to treat amyotrophic lateral sclerosis.

Edaravone may also be used for purposes not listed in this medication guide.

Warnings

Edaravone can cause serious allergic reactions. Get emergency medical help if you have hives, itching, trouble breathing, swelling in your face or throat, or if you feel light-headed.

Before taking this medicine

You should not be treated with edaravone if you are allergic to it.

To make sure edaravone is safe for you, tell your doctor if you have ever had:

It is not known whether edaravone will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether edaravone passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

How is edaravone given?

Edaravone is injected into a vein through an IV. A healthcare provider will give you this injection.

Edaravone is usually given in a 28-day treatment cycle. You may need to use the medicine only during the first 2 weeks of each cycle. Your doctor will determine how long to treat you with edaravone.

This medicine must be given slowly and the IV infusion can take at least 60 minutes to complete.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your edaravone injection.

What happens if I overdose?

Since edaravone is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving edaravone?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Edaravone side effects

Edaravone can cause serious allergic reactions. The symptoms may not appear until after your IV infusion is finished.

Get emergency medical help if you have signs of an allergic reaction: hives, itching; wheezing, difficult breathing; feeling light-headed; swelling...