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Edoxaban
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Edoxaban

Generic name: edoxaban [ e-DOX-a-ban ]
Brand name: Savaysa
Dosage form: oral tablet (15 mg; 30 mg; 60 mg)
Drug class:Factor Xa inhibitors

Medically reviewed by Drugs.com on Jun 17, 2021. Written by Cerner Multum.

What is edoxaban?

Edoxaban blocks the activity of certain clotting substances in the blood.

Edoxaban is used to lower the risk of stroke caused by a blood clot in people with a heart rhythm disorder called atrial fibrillation. edoxaban is used when the atrial fibrillation is not caused by a heart valve problem.

Edoxaban is also used to treat a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism). A DVT can sometimes occur after a person has been treated with an injectable blood thinner for 5 to 10 days.

Edoxaban may also be used for purposes not listed in this medication guide.

Warnings

Edoxaban can cause you to bleed more easily. Call your doctor at once if you have signs of bleeding such as: bleeding gums, nosebleeds, heavy menstrual periods or abnormal vaginal bleeding, blood in your urine, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Many other drugs can increase your risk of bleeding when used with edoxaban. Tell your doctor about all medicines you have recently used.

Edoxaban can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). Tell any doctor who treats you that you are taking edoxaban.

Do not stop taking edoxaban without first talking to your doctor. Stopping suddenly can increase your risk of blood clot or stroke.

Before taking this medicine

You should not use edoxaban if you are allergic to it, or if you have active or uncontrolled bleeding.

Edoxaban can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could cause long-term paralysis, and may be more likely to occur if:

  • you have a genetic spinal defect;

  • you have a spinal catheter in place;

  • you have a history of spinal surgery or repeated spinal taps;

  • you have recently had a spinal tap or epidural anesthesia;

  • you are taking an NSAID--Advil, Aleve, Motrin, and others; or

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