Efavirenz, emtricitabine, and tenofovir

Generic name: efavirenz, emtricitabine, and tenofovir [ ef-AV-ir-enz, em-trye-SYE-ta-been, and-ten-OF-oh-vir ]
Brand name: Atripla
Dosage form: oral tablet (600 mg-200 mg-300 mg)
Drug class:Antiviral combinations

Medically reviewed by Drugs.com on Feb 26, 2021. Written by Cerner Multum.

What is efavirenz, emtricitabine, and tenofovir (Atripla)?

Atripla is a combination antiviral medication that prevents human immunodeficiency virus (HIV) from reproducing in your body.

Atripla is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Atripla is not a cure for HIV or AIDS. Atripla is for use in adults and children who are at least 12 years old and weigh at least 88 pounds (40 kilograms).

Atripla may also be used for purposes not listed in this medication guide.

Warnings

Do not take Atripla together with adefovir, atazanavir, voriconazole, or medications that contain emtricitabine, lamivudine, or tenofovir.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

Atripla can cause severe or fatal liver problems. Call your doctor at once if you have symptoms such as stomach pain or swelling, loss of appetite, dark urine, or yellowing of your skin or eyes.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.

If you've ever had hepatitis B, it may become active or get worse after you stop using Atripla. You may need frequent liver function tests for several months.

Before taking this medicine

You should not take efavirenz, emtricitabine, and tenofovir if you are allergic to efavirenz (Sustiva), emtricitabine (Emtriva), or tenofovir (Viread).

Do not take Atripla together with adefovir, atazanavir, voriconazole, or any medications that contain emtricitabine, lamivudine, or tenofovir (such as Combivir, Complera, Descovy, Epivir, Epzicom,