Efavirenz, lamivudine, and tenofovir
Generic name: efavirenz, lamivudine, and tenofovir [ ef-AV-ir-enz, la-MIV-ue-deen, and-ten-OF-oh-vir ]
Brand names: Symfi, Symfi Lo
Dosage form: oral tablet (400 mg-300 mg-300 mg; 600 mg-300 mg-300 mg)
Drug class:Antiviral combinations
What is efavirenz, lamivudine, and tenofovir?
Efavirenz, lamivudine, and tenofovir is a combination antiviral medicine that is used to treat human immunodeficiency virus (HIV). HIV is the virus that can cause acquired immunodeficiency syndrome (AIDS). efavirenz, lamivudine, and tenofovir is not a cure for HIV or AIDS.
Symfi is for use in adults and children who weigh at least 88 pounds (40 kilograms).
Symfi Lo is for use in adults and children who weigh at least 77 pounds (35 kilograms).
Efavirenz, lamivudine, and tenofovir may also be used for purposes not listed in this medication guide.
Warnings
If you've ever had hepatitis B, it may become active or get worse after you stop using this medicine. You may need frequent liver function tests for several months.
Do not change your dose or stop taking this medicine without your doctor's advice.
Before taking this medicine
You should not use this medicine if:
you also take elbasvir and grazoprevir (for hepatitis C); or
you are allergic to any antiviral combination medicine that contains efavirenz, lamivudine, or tenofovir.
Tell your doctor if you have ever had:
liver disease (especially hepatitis B or C); or
kidney disease (or if you are on dialysis);
heart problems;
long QT syndrome (in you or a family member);
drug or alcohol addiction;
a seizure; or
fractures or other problems with your bones.
You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you are overweight or if you are a woman. Ask your doctor about your risk.
You may need to have a negative pregnancy test before starting this treatment.
Do not use this medicine if you are pregnant. It could harm the unborn baby or cause birth defects. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 12 weeks after your last dose.
Use two forms of birth control to prevent...
