Elbasvir and grazoprevir

Generic name: elbasvir and grazoprevir [ ELB-as-vir-and-graz-OH-pre-vir ]
Brand name: Zepatier
Dosage form: oral tablet (50 mg-100 mg)
Drug class:Antiviral combinations

Medically reviewed by Drugs.com on Jul 7, 2020. Written by Cerner Multum.

What is elbasvir and grazoprevir?

Elbasvir and grazoprevir are antiviral medicines that prevent hepatitis C (HCV) from multiplying in your body.

Elbasvir and grazoprevir is a combination medicine used to treat chronic hepatitis C in adults. elbasvir and grazoprevir is sometimes given together with another drug called ribavirin.

Elbasvir and grazoprevir treats specific genotypes of hepatitis C, and only in certain people. Use only the medications prescribed for you. Do not share your medicine with other people.

Elbasvir and grazoprevir is sometimes used in people who also have HIV. This medicine is not a treatment for HIV or AIDS.

Elbasvir and grazoprevir may also be used for purposes not listed in this medication guide.

Warnings

You should not use this medicine if you have moderate or severe liver disease.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

If you've ever had hepatitis B, using elbasvir and grazoprevir can cause this virus to become active or get worse. Tell your doctor if you don't feel well and you have right-sided upper stomach pain, vomiting, loss of appetite, or yellowing of your skin or eyes.

Before taking this medicine

You should not use elbasvir and grazoprevir if you are allergic to elbasvir or grazoprevir, or if you have:

• moderate or severe liver disease.

When taking elbasvir and grazoprevir with ribavirin: To make sure all medicines are safe for you, tell your doctor about all your medical conditions, and if you are pregnant or breastfeeding.

Many drugs can interact and cause dangerous effects. Some drugs should not be used together with elbasvir and grazoprevir. Your doctor may change your treatment plan if you also use:

• cyclosporine;

• rifampin;

• St. John's wort;

• HIV or AIDS medication--atazanavir, darunavir, efavirenz, lopinavir, saquinavir, tipranavir; or

• seizure medicine--carbamazepine, phenytoi...