Eliglustat

Generic name: eliglustat [ EL-i-GLOO-stat ]
Brand name: Cerdelga
Dosage form: oral capsule (84 mg)
Drug class:Miscellaneous metabolic agents

Medically reviewed by Drugs.com on Sep 23, 2021. Written by Cerner Multum.

What is eliglustat?

Eliglustat reduces the formation of a certain protein in the body in people with type 1 Gaucher disease.

Gaucher disease is a genetic condition in which the body lacks the enzyme needed to break down certain fatty materials (lipids). Lipids can build up in the body, causing symptoms such as easy bruising or bleeding, weakness, anemia, bone or joint pain, enlarged liver or spleen, or weakened bones that are easily fractured.

Eliglustat is used to treat mild to moderate type 1 Gaucher disease in adults. Eliglustat is used only if a specific liver enzyme (2D6) in your body breaks down or metabolizes drugs at a certain rate.

Eliglustat may improve the condition of the liver, spleen, bones, and blood cells in people with Type I Gaucher disease. However, eliglustat is not a cure for this condition.

Eliglustat may also be used for purposes not listed in this medication guide.

Warnings

You should not use eliglustat if you have severe liver or kidney disease.

Eliglustat can cause a serious heart problem, especially if you use certain other medicines at the same time. Tell your doctor about all medicines you use.

Before taking this medicine

Sometimes it is not safe to use certain medications at the same time. Some drugs can raise or lower your blood levels of eliglustat, which may cause side effects or make eliglustat less effective. Eliglustat can also affect blood levels of certain other drugs, making them less effective or increasing side effects.

Your doctor may need to change your treatment plan if you use any of the following drugs:

• St. John's wort;

• antifungal medicine;

• tuberculosis medicine;

• seizure medicine;

• heart or blood pressure medications;

• an antidepressant; or

• medicine to treat a mental illness.

You should not use eliglustat if you are allergic to it, or if you have:

• severe liver disease.

Tell your doctor if you have ever had:

• long QT syndrome or other heart rhythm disorder;

• heart disease or a heart attack;

• liver disease; or

• kidney disease.

It is not known whether eliglustat will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breast-feed while using this medicine.

Eliglust...