Albutein 25%

Generic name:albumin (human)
Dosage form: injection
Drug class:Plasma expanders

Medically reviewed by Drugs.com. Last updated on Jun 21, 2021.

1. INDICATIONS AND USAGE

Albumin (Human) U.S.P., Albutein® 25% Solution is indicated:

1. For treatment of hypovolemic shock.1,2
2. As an adjunct in hemodialysis for patients undergoing long-term dialysis or for those patients who are fluid-overloaded and cannot tolerate substantial volumes of salt solution for therapy of shock or hypotension.3
3. In cardiopulmonary bypass procedures; however, the optimum regimen of fluids has not been established.

Conditions in which Albutein® 25% MAY BE indicated:

• Adult respiratory distress syndrome (ARDS).3,4
• Major injury or surgery resulting in increased albumin loss or inadequate synthesis.3,5
• Acute nephrosis not responding to cyclophosphamide or steroid therapy. Steroid therapy may increase edema which may respond to combined therapy of albumin with a diuretic.3
• Acute liver failure or ascites where the therapeutic use is regulated by the individual circumstances.3

Unless the pathologic condition responsible for hypoalbuminemia can be corrected, administration of albumin can afford only symptomatic relief. There is NO valid reason for the use of albumin as an intravenous nutrient.

2. DOSAGE AND ADMINISTRATION

Albutein® 25% is administered intravenously. The total dosage will vary with the individual. In adults, an initial infusion of 100 mL is suggested. Additional amounts may be administered as clinically indicated.

In the treatment of the patient in shock with greatly reduced blood volume, Albutein® 25% may be administered as rapidly as necessary in order to improve the clinical condition and restore normal blood volume. This may be repeated in 15-30 minutes if the initial dose fails to prove adequate. In the pa...