Endometrin

Generic name:progesterone vaginal [ proe-JESS-te-rone-VAJ-in-al ]
Drug class:Progestins

Medically reviewed by Drugs.com. Last updated on Jun 14, 2021.

What is Endometrin?

Endometrin is a vaginal insert containing progesterone 100mg. Progesterone is a female hormone important for ovulation and menstruation. Progesterone causes changes in the lining of your uterus, making it easier for a fertilized egg to attach to the uterus at the beginning of pregnancy. Progesterone then helps your body maintain the pregnancy.

Endometrin is used in fertility treatment as part of Assisted Reproductive Technology (ART) for women unable to get pregnant due to a lack of natural progesterone in the body.

Endometrin may also be used for purposes not listed in this medication guide.

Warnings

You should not use Endometrin if you have: a history of stroke or blood clot, circulation problems, liver disease, breast or uterine cancer, abnormal vaginal bleeding, or if you have recently had a tubal pregnancy or an incomplete abortion.

When used as part of fertility treatment, Endometrin may be given for up to 10 weeks into a pregnancy. Following your dosing schedule is very important for this medication to be effective. Try not to miss any doses.

Endometrin can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Before taking this medicine

You should not use Endometrin if you have ever had an allergic reaction to progesterone, or if you have:

• a history of stroke, blood clot, or circulation problems;

• breast or uterine cancer;

• abnormal vaginal bleeding;

• liver disease; or

• if you have recently had a tubal pregnancy or an incomplete or "missed" abortion.

To make sure Endometrin is safe for you, tell your doctor if you have:

• high blood pressure, heart disease, congestive heart failure;

• migraines,

• asthma;

• kidney disease;

• seizures or epilepsy;

• a history of depression; or

• risk factors for coronary artery disease (such as diabetes, lupus, high cholesterol, family history of coronary artery disease, smoking, or being overweight).

Using Endometrin can increase your risk of blood clots, stroke, heart attack, or breast cancer. Talk to your doctor about this risk.

Do not use Endometrin if you are pregnant, unless you are using this medicine as part of your fertility treatment.

Tell your doctor if you become pregnant during treatment.

Endometrin can pass into breast milk and may harm a nursing baby.

How should I use Endometrin?

Use Endometrin exactly as it was prescribed for you. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Do not take by mouth. Endometrin is for use only in the vagina.

Insert this medicine directly into the vagina using only the applicator provided. Use a disposable applicator onl...