Enfortumab vedotin
Generic name: enfortumab vedotin [ en-FORT-ue-mab-ve-DOE-tin ]
Brand name: Padcev
Dosage form: intravenous powder for injection (ejfv 20 mg; ejfv 30 mg)
Drug class:Miscellaneous antineoplastics
What is enfortumab vedotin?
Enfortumab vedotin is used to treat cancer of the bladder or urinary tract that has spread to other parts of the body (metastatic), or cannot be removed with surgery.
Enfortumab vedotin is usually given after other treatments such as immunotherapy and platinum cancer medicine, or if you are unable to receive platinum cancer medicine.
Enfortumab vedotin may also be used for purposes not listed in this medication guide.
Warnings
enfortumab vedotin can cause a severe or life-threatening skin rash. Get emergency medical help if you have a worsening rash with itching, blistering, peeling, skin lesions that look like rings, a fever or flu-like symptoms, swollen glands, or painful sores in your mouth, nose, throat, or genital area.
Before taking this medicine
Tell your doctor if you have ever had:
numbness or tingling in your hands or feet;
diabetes;
high blood sugar;
Enfortumab vedotin can harm an unborn baby if the mother or the father is using this medicine.
If you are a woman, you may need a pregnancy test to make sure you are not pregnant. Use birth control while using this medicine and for at least 2 months after your last dose.
If you are a man, use birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.
It may be harder for you to get a woman pregnant while you are using this medicine. You should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.
Tell your doctor right away if a pregnancy occurs.
Do not breastfeed while using this medicine, and for at least 3 weeks after your last dose.
How is enfortumab vedotin given?
Enfortumab vedotin is injected into a vein by a healthcare provider.
enfortumab vedotin must be given slowly over 30 minutes.
Tell your medical caregivers if you feel any burning or pain when enfortumab vedotin is injected.
Enfortumab vedotin is given in a 28-day treatment cycle. You will receive an injection only on certain days of this cycle. Your doctor will determine how many cycles you need.
This medicine can cause a severe or life-threatening skin rash, especially during the first treatment cycle. Call your doc...
