Enlon-Plus
Generic name: edrophonium chloride and atrophine sulfate
Dosage form: injection, solution
Drug class:Cholinergic muscle stimulants
Medically reviewed by Drugs.com. Last updated on Dec 22, 2021.
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The Enlon-Plus brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Enlon-Plus Description
Enlon-Plus (edrophonium chloride, USP and atropine sulfate, USP) Injection, for intravenous use, is a sterile, nonpyrogenic, nondepolarizing neuromuscular relaxant antagonist. Enlon-Plus is a combination drug containing a rapid acting acetylcholinesterase inhibitor, edrophonium chloride, and an anticholinergic, atropine sulfate. Chemically, edrophonium chloride is ethyl (m-hydroxyphenyl) dimethylammonium chloride; its structural formula is:
Molecular Formula: C10H16ClNO
Molecular Weight: 201.70
Chemically, atropine sulfate is: endo-(±)-alpha-(hydroxymethyl)-8-methyl-8-azabicyclo [3.2.1]oct-3-yl benzeneacetate sulfate (2:1) monohydrate. Its structural formula is:
Molecular Formula: (C17H23NO3)2•H2SO4•H2O
Molecular Weight: 694.84
Enlon-Plus contains in each mL of sterile solution:
5 mL Ampule: 10 mg edrophonium chloride and 0.14 mg atropine sulfate compounded with 2.0 mg sodium sulfite as a preservative and buffered with sodium citrate and citric acid. The pH range is 4.0-5.0.
