Entadfi
Generic name:finasteride and tadalafil
Dosage form: capsules
What Is Entadfi?
Entadfi is a prescription medicine taken by mouth for the treatment of men with symptoms of benign prostatic hyperplasia (BPH).
BPH is a condition that happens in men, where the prostate gland enlarges which can cause urinary symptoms.
Entadfi is for use by men only.
Important information
Entadfi can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines. You could get dizzy, faint, or have a heart attack or stroke. Never take Entadfi with any nitrate or guanylate cyclase stimulator medicines.
Do not take Entadfi if you take any medicines called “nitrates.” Nitrates are commonly used to treat angina. Angina is a symptom of heart disease and can cause pain in your chest, jaw, or down your arm.
- Medicines called nitrates include nitroglycerin that is found in tablets, sprays, ointments, pastes, or patches. Nitrates can also be found in other medicines such as isosorbide dinitrate or isosorbide mononitrate. Some recreational drugs called “poppers” also contain nitrates, such as amyl nitrite and butyl nitrite.
Do not take Entadfi if you take medicines called guanylate cyclase stimulators which include:
- Riociguat (Adempas®) a medicine that treats pulmonary arterial hypertension and chronic-thromboembolic pulmonary hypertension.
Ask your healthcare provider or pharmacist if you are not sure if any of your medicines are nitrates or guanylate cyclase stimulators, such as riociguat.
Do not take Entadfi if you are a woman who is pregnant or may potentially be pregnant.
- Entadfi may harm your unborn baby. Do not touch or handle crushed or open Entadfi capsules (See Who Should Not Take Entadfi? and Warning about Entadfi and pregnancy).
Tell all of your healthcare providers that you take Entadfi. If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took Entadfi.
After taking a single capsule, the tadalafil active ingredient of Entadfi remains in your body for more than 2 days. The active ingredient can remain longer if you have problems with your kidneys or liver, or you are taking certain other medications (see What other drugs will affect Entadfi?).
Stop sexual activity and get medical help right away if you get symptoms such as chest pain, dizziness, or nausea during sex. Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease.
See also Entadfi side effects.
You should see your doctor regularly while taking Entadfi. Follow your doctor's advice about when to have these checkups.
Checking for prostate cancer. Your doctor has prescribed Entadfi for BPH and not for treatment of prostate cancer - but a man can have BPH and prostate cancer at the same time. Your doctor may continue checking for prostate cancer while you take Entadfi.
