Generic name:sacubitril and valsartan [ sak-UE-bi-tril-and-val-SAR-tan ]
Drug class:Angiotensin receptor blockers and neprilysin inhibitors
What is Entresto?
Entresto contains a combination of sacubitril and valsartan. Sacubitril is a blood pressure medicine. It works by increasing the levels of certain proteins in the body that can dilate (widen) blood vessels. This helps lower blood pressure by reducing sodium levels.
Valsartan is an angiotensin II receptor blocker (sometimes called an ARB). Valsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
Entresto is used in adults with chronic heart failure. This medicine helps lower the risk of needing to be hospitalized when symptoms get worse, and helps lower the risk of death from heart failure.
Entresto is also used to treat heart failure in children who are at least 1 year old.
Entresto is usually given together with other heart medications.
Warnings
Do not use Entresto if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Entresto can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.
If you have diabetes, do not use Entresto together with any medication that contains aliskiren (Tekturna, Tekamlo).
Before taking this medicine
You should not use Entresto if you are allergic to sacubitril or valsartan (Diovan), or if you have ever had a severe allergic reaction to a blood pressure medication such as:
an ACE inhibitor - benazepril,...
