Epiklor

Generic name:potassium chloride
Dosage form: powder, for oral solution
Drug class:Minerals and electrolytes

Medically reviewed by Drugs.com. Last updated on Jul 22, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Epiklor Description

Fruit-flavored Epiklor™ and Epiklor™/25 Powder (Potassium Chloride for Oral Solution, USP) are oral potassium supplements offered as powder for reconstitution in individual packets. Each packet of Epiklor™ powder contains potassium 20 mEq and chloride 20 mEq provided by potassium chloride 1.5 g. Each packet of Epiklor™/25 powder contains potassium 25 mEq and chloride 25 mEq provided by potassium chloride 1.875 g. Epiklor™ and Epiklor™/25 are sugar-free and saccharine-free.

Inactive ingredients: FD&C Yellow #6, sucralose, silicon dioxide, maltodextrin, citric acid and orange flavor.

Epiklor - Clinical Pharmacology

Potassium ion is the principal intracellular cation of most body tissues. Potassium ions participate in a number of essential physiological processes, including the maintenance of intracellular tonicity, the transmission of nerve impulses, the contraction of cardiac, skeletal, and smooth muscle and the maintenance of normal renal function.

Potassium depletion may occur whenever the rate of potassium loss through renal excretion and/or loss from the gastrointestinal tract exceeds the rate of potassium intake. Such depletion usually develops slowly as a consequence of prolonged therapy with oral diuretics, primary or secondary hyperaldosteronism, diabetic ketoacidosis, severe diarrhea, or inadequate replacement of potassium in patients on prolonged parenteral nutrition. Potassium depletion due to these causes is usually accompanied by a concomitant deficiency of chloride and is manifested by hypokalemia and metabolic alkalosis. Potassium depletion may produce weakness, fatigue, disturbances of cardiac rhythm (primarily ectopic beats), prominent U-waves in the electro-cardiogram, and in advanced cases flaccid paralysis and/or impair ability to concentrate urine.

Potassium depletion associated with metabolic alkalosis is managed by correcting the fundamental causes ...