Eplerenone

Generic name: eplerenone [ ep-LER-e-none ]
Brand name: Inspra
Dosage form: oral tablet (25 mg; 50 mg)
Drug classes:Aldosterone receptor antagonists, Potassium-sparing diuretics

Medically reviewed by Drugs.com on Mar 8, 2022. Written by Cerner Multum.

What is eplerenone?

Eplerenone is used to lower the risk of death from heart failure after a heart attack.

Eplerenone is also used to treat high blood pressure (hypertension).

Eplerenone may also be used for purposes not listed in this medication guide.

Warnings

You may not be able to take eplerenone if you have severe kidney disease, high potassium levels in your blood, or type 2 diabetes with increased levels of albumin (a protein) in your urine.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

Before taking this medicine

You may not be able to take this medicine if you are allergic to eplerenone, or if you have:

• high potassium levels in your blood (hyperkalemia);

• severe kidney disease; or

• type 2 diabetes with increased levels of albumin (a protein) in your urine.

Some medicines can cause unwanted or dangerous effects when used with eplerenone. Your doctor may change your treatment plan if you also use:

• nefazodone;

• a potassium supplement;