Eptifibatide
Generic name: eptifibatide [ ep-ti-FYE-ba-tide ]
Brand name: Integrilin
Dosage form: intravenous solution (0.75 mg/mL; 2 mg/mL)
Drug class:Glycoprotein platelet inhibitors
What is eptifibatide?
Eptifibatide helps to prevent platelets in your blood from sticking together and forming a blood clot. An unwanted blood clot can occur with certain heart or blood vessel conditions.
Eptifibatide is used to prevent blood clots or heart attack in people with severe chest pain or other conditions, and in those who are undergoing a procedure called angioplasty (to open blocked arteries).
Eptifibatide may also be used for purposes not listed in this medication guide.
Warnings
You should not receive eptifibatide if you are also being treated with similar medications such as abciximab (ReoPro) or tirofiban (Aggrastat).
You should not receive eptifibatide if: you have severe or uncontrolled high blood pressure; you are on dialysis due to kidney failure; you have a bleeding or blood-clotting disorder; you had a stroke or any type of bleeding within the past 30 days; or you had any type of surgery, injury, or medical emergency within the past 6 weeks.
Tell your doctor if you are pregnant or plan to become pregnant during treatment with eptifibatide and aspirin.
Before taking this medicine
You should not use eptifibatide if you are allergic to it, or if you have:
kidney failure and you are on dialysis;
severe or uncontrolled high blood pressure;
a bleeding or blood-clotting disorder, such as hemophilia or thrombocytopenia;
if you have had a stroke or any type of bleeding within the past 30 days;
if you have had any type of surgery, injury, or medical emergency within the past 6 weeks; or
if you have or will soon receive treatment with similar medications such as abciximab (ReoPro) or tirofiban (Aggrastat).
To make sure you can safely receive eptifibatide, tell your doctor if you have kidney disease.
Eptifibatide is not expected to be harmful to an unborn baby. However, aspirin is sometimes given with eptifibatide, and aspirin can cause bleeding when it is taken during the last 3 months of pregnancy. Aspirin can also cause side effects in a newborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether eptifibatide passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
