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Equidone Oral Gel
  • Professionals
  • FDA PI

Equidone Oral Gel

Generic name: domperidone gel
Dosage form: FOR ANIMAL USE ONLY

CAUTION

Federal law (USA) restricts this drug to use by or on the order of a licensed veterinarian.

For oral use in horses only.

Equidone Oral Gel Description

Domperidone is D2 dopamine receptor antagonist. Chemically, domperidone is 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one.

The structural formula is:

Molecular Formula: C22H24CIN5O2 Molecular Weight: 425.91

INDICATIONS

For prevention of fescue toxicosis in periparturient mares.

Equidone Oral Gel Dosage and Administration

Orally administer 0.5 mg/lb (1.1 mg/kg) once daily starting 10 to 15 days prior to Expected Foaling Date (EFD). Treatment may be continued for up to 5 days after foaling if mares are not producing adequate milk after foaling.

DIRECTIONS FOR ADMINISTRATION

  1. Determine the appropriate dose for the body weight of the mare based on the dosing table below. One cc will treat 220 lb (100 kg) of body weight.
    Table 1. Dosing Table
    Weight
    (lb)
    Weight
    (kg)
    ccDomperidone
    (mg)
    550-660250-3003330
    661-880301-4004440
    881-1100