Equidone Oral Gel
Generic name: domperidone gel
Dosage form: FOR ANIMAL USE ONLY
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CAUTION
Federal law (USA) restricts this drug to use by or on the order of a licensed veterinarian.
For oral use in horses only.
Equidone Oral Gel Description
Domperidone is D2 dopamine receptor antagonist. Chemically, domperidone is 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one.
The structural formula is:
Molecular Formula: C22H24CIN5O2 Molecular Weight: 425.91
INDICATIONS
For prevention of fescue toxicosis in periparturient mares.
Equidone Oral Gel Dosage and Administration
Orally administer 0.5 mg/lb (1.1 mg/kg) once daily starting 10 to 15 days prior to Expected Foaling Date (EFD). Treatment may be continued for up to 5 days after foaling if mares are not producing adequate milk after foaling.
DIRECTIONS FOR ADMINISTRATION
- Determine the appropriate dose for the body weight of the mare based on the dosing table below. One cc will treat 220 lb (100 kg) of body weight.
Table 1. Dosing Table Weight
(lb)Weight
(kg)cc Domperidone
(mg)550-660 250-300 3 330 661-880 301-400 4 440 881-1100