Esmolol Injection
Generic name: esmolol hydrochloride
Dosage form: injection, solution
Drug classes:Cardioselective beta blockers, Group II antiarrhythmics
Medically reviewed by Drugs.com. Last updated on Oct 1, 2021.
On This Page
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Drug Interactions
- Use In Specific Populations
- Overdosage
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- Clinical Studies
- How Supplied/Storage and Handling
- Patient Counseling Information
INDICATIONS AND USAGE
Supraventricular Tachycardia or Noncompensatory Sinus Tachycardia
Esmolol hydrochloride in sodium chloride injection is indicated for the rapid control of ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other emergent circumstances where short term control of ventricular rate with a short-acting agent is desirable. Esmolol hydrochloride in sodium chloride injection is also indicated in noncompensatory sinus tachycardia where, in the physician’s judgment, the rapid heart rate requires specific intervention. Esmolol hydrochloride in sodium chloride injection is intended for short-term use.
Intraoperative and Postoperative Tachycardia and Hypertension
Esmolol hydrochloride in sodium chloride injection is indicated for the short-term treatment of tachycardia and hypertension that occur during induction and tracheal intubation, during surgery, on emergence from anesthesia and in the postoperative period, when in the physician’s judgment such specific intervention is considered indicated.
Use of esmolol hydrochloride in sodium chloride injection to prevent such events is not recommended.
DOSAGE AND ADMINISTRATION
Dosing for the Treatment of Supraventricular Tachycardia or Noncompensatory Sinus Tachycardia
Esmolol hydrochloride in sodium chloride injection is administered by continuous intravenous infusion with or without a loading dose. Additional loading doses and/or titration of the maintenance infusion (step-wise dosing) may be necessary based on desired ventricular response.
