Estradiol and norethindrone (transdermal)
Generic name: estradiol and norethindrone (transdermal) [ ES-tra-DYE-ol-and-nor-ETH-in-drone ]
Brand name: Combipatch
Dosage form: transdermal film, extended release (0.05 mg-0.14 mg/24 hours; 0.05 mg-0.25 mg/24 hours)
Drug class:Sex hormone combinations
What are estradiol and norethindrone?
Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body.
Norethindrone is a form of progesterone, a female hormone important for regulating ovulation and menstruation.
Estradiol and norethindrone transdermal (skin patch) is a combination medicine used to treat menopause symptoms such as hot flashes and vaginal changes (itching, burning, dryness). estradiol and norethindrone is also used before menopause to treat a lack of estrogen caused by conditions such as hypogonadism, primary ovarian failure, or surgical removal of the ovaries.
Estradiol and norethindrone may also be used for purposes not listed in this medication guide.
Warnings
You should not use this medicine if you have: undiagnosed vaginal bleeding, liver disease, a bleeding disorder, if you will have major surgery, or if you have ever had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina.
Do not use if you are pregnant.
This medicine may increase your risk of developing a condition that may lead to uterine cancer. Report any unusual vaginal bleeding right away.
Using this medicine can increase your risk of blood clots, stroke, heart attack, or cancer of the breast, uterus, or ovaries. Estradiol and norethindrone should not be used to prevent heart disease, stroke, or dementia.
Before taking this medicine
You should not use estradiol and norethindrone if you are allergic to estradiol or norethindrone, or if you have:
unusual vaginal bleeding that has not been checked by a doctor;
liver disease;
a bleeding disorder;
a history of heart attack, stroke, or blood clot; or
a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina.
Do not use estradiol and norethindrone if you are pregnant. Tell your doctor right away if you become pregnant during treatment.
Using this medicine can increase your risk of blood clots, stroke,...
