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Estradiol and progesterone
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Estradiol and progesterone

Generic name: estradiol and progesterone [ ES-tra-DYE-ol-and-pro-JES-ter-one ]
Brand name: Bijuva
Dosage form: oral capsule (1 mg-100 mg)
Drug class:Sex hormone combinations

Medically reviewed by Drugs.com on Feb 8, 2022. Written by Cerner Multum.

What is estradiol and progesterone?

Estradiol (a form of estrogen) and progesterone are female hormones.

Estradiol and progesterone is a combination medicine used to treat moderate to severe hot flashes caused by menopause.

estradiol and progesterone is for use only in a woman who has not had her uterus removed.

Estradiol and progesterone may also be used for purposes not listed in this medication guide.

Warnings

You should not use this medicine if your uterus has been removed, or if you have: undiagnosed vaginal bleeding, liver disease, a bleeding disorder, if you will have major surgery, or if you have ever had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina.

Estradiol may increase your risk of developing a condition that may lead to uterine cancer. Call your doctor if you have any vaginal bleeding.

Using this medicine can increase your risk of blood clots, stroke, heart attack, or cancer of the breast, uterus, or ovaries. Estradiol and progesterone should not be used to prevent heart disease, stroke, or dementia.

Before taking this medicine

You should not take estradiol and progesterone if your uterus has been removed, or if you have:

  • unusual vaginal bleeding that has not been checked by a doctor;

  • liver disease;

  • an increased risk of having blood clots due to a heart problem or a hereditary blood disorder;

  • a history of heart attack, stroke, or blood clot; or

  • a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina.

Tell your doctor if you have ever had:

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