Estradiol, norethindrone, and relugolix
Generic name: estradiol, norethindrone, and relugolix [ ES-tra-DYE-ol, nor-ETH-in-drone, and-REL-ue-GOE-lix ]
Brand name: Myfembree
Dosage form: oral tablet (1 mg-0.5 mg-40 mg)
Drug class:Sex hormone combinations
What is estradiol, norethindrone, and relugolix (Myfembree)?
Estradiol, norethindrone, and relugolix (Myfembree) is used to control heavy menstrual bleeding cause by uterine fibroids in premenopausal women.
Myfembree may also be used for purposes not listed in this medication guide.
Warnings
Using this medicine can increase your risk of blood clots, stroke, or heart attack. You are even more at risk if you are over 35 years of age, you smoke, and you have uncontrolled high blood pressure.
Smoking can greatly increase your risk of blood clots, stroke, or heart attack. You should not use this medicine if you smoke and are older than 35 years of age.
Stop taking this medicine and get medical help at once if you have signs of a heart attack or stroke: chest pain, sudden numbness or weakness, slurred speech, severe headache, vision problems, leg pain or swelling, feeling short of breath.
Before taking this medicine
You should not use Myfembree if you are allergic to estradiol, norethindrone, or relugolix, or if you have:
untreated or uncontrolled high blood pressure;
heart problems (heart valve disorder or heart rhythm disorder);
a history of heart attack, stroke, or blood clot;
blood circulation problems;
an increased risk of having blood clots due to a hereditary blood disorder;
diabetes with damage to your kidneys, eyes, nerves, or blood vessels;
a history of hormone-related cancer, or cancer of the breast, uterus/cervix, or vagina;
unusual vaginal bleeding that has not been checked by a doctor;
severe migraine headaches (with aura, numbness, weakness, or vision changes), especially if you are older than 35;
osteoporosis; or
Tell your doctor if you ha...
