Estrasorb

Generic name:estradiol topical (for use on skin) [ ess-tra-DYE-ol-TOP-ik-al ]
Drug class:Estrogens

Medically reviewed by Philip Thornton, DipPharm. Last updated on Jun 14, 2021.

What is Estrasorb?

Estrasorb is topical emulsion containing estradiol. Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body.

Estrasorb is used to after menopause to reduce moderate to severe hot flashes. The ovaries normally stop making estrogens when a woman is between 45 to 55 years old. When the estrogen levels begin dropping, some women develop very uncomfortable symptoms, such as feelings of warmth in the face, neck, and chest, or sudden strong feelings of heat and sweating (“hot flashes” or “hot flushes”). In some women, the symptoms are mild, and they will not need estrogens. In other women, symptoms can be more severe.

Estrasorb may also be used for purposes not listed in this medication guide.

Warnings

You should not use Estrasorb if you have any of the following conditions: a history of heart attack, stroke, or blood clot, a bleeding or blood-clotting disorder, liver disease, abnormal vaginal bleeding, history of an allergic reaction to estradiol topical, or a hormone-related cancer such as breast or uterine cancer.

Do not use Estrasorb if you are pregnant.

Estradiol may increase your risk of developing a condition that may lead to uterine cancer. Call your doctor at once if you have any unusual vaginal bleeding while using Estrasorb.

Children should avoid coming into contact with skin areas where you have applied Estrasorb. Topical estradiol is absorbed through the skin and can cause side effects in a child who comes into contact with Estrasorb or with skin where the medicine was applied.

Estradiol should not be used to prevent heart disease, stroke, or dementia, because this medicine may actually increase your risk of developing these conditions. Long-term use may also increase your risk of breast cancer or blood clot.

Before this medicine

You should not use Estrasorb if you have:

• abnormal vaginal bleeding that has not been checked by a doctor;

• any type of breast, uterine, or hormone-dependent cancer;

• a history of heart attack, stroke, or blood clot (especially in your lung or your lower body);

• liver disease;

• a bleeding or blood-clotting disorder;

• if you are pregnant or may become pregnant; or

• if you have ever had an allergic reaction to estradiol topical.

Estradiol will not prevent heart disease, heart attack, stroke, breast cancer, or dementia, and may actually increase your risk of developing these conditions. Estradiol may also increase your risk of uterine or ovarian cancer. Tal...