Generic name:esterified estrogens and methyltestosterone (oral route) [ es-TER-i-fide-ES-troe-jenz, meth-il-tes-TOS-ter-one ]
Drug class:Sex hormone combinations
Medically reviewed by Drugs.com. Last updated on Apr 21, 2022.
Estrogens increase the risk of endometrial cancer; monitor for abnormal vaginal bleeding. Estrogens with or without progestins should not be used for the prevention of cardiovascular disease or dementia. Increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women (50 to 79 years) have been reported. An increased risk of developing probable dementia in postmenopausal women 65 years or older has also been reported. This product contains an estrogen and androgen, not a progestin. This combination should not be used during a known or suspected pregnancy .
The Estratest brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Commonly used brand name(s)
In the U.S.
- Covaryx
- Covaryx HS
- Essian
- Estratest
- Menogen
- Syntest D.S.
- Syntest H.S.
Available Dosage Forms:
- Tablet
Therapeutic Class: Estrogen/Androgen Combination
Pharmacologic Class: Estrogen
Uses for Estratest
Esterified estrogens and methyltestosterone combination is used to treat the symptoms of menopause in patients who did not get relief after being treated with estrogens alone. These symptoms may include a feeling of heat, sweating, and warmth in the face, neck, or chest ("hot flashes"); and dryness, burning, and itching in the vagina.
Esterified estrogens are a man-made mixture of estrogens. Estrogen is a hormone that is produced by the body in greater amounts in females. It is necessary for normal sexual development of the female and for regulation of the menstrual cycle dur..
