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Estrogen/androgen combination Oral, Parenteral
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Estrogen/androgen combination

Class Name: estrogen/androgen combination (Oral route, Parenteral route)

Commonly used brand name(s)

In the U.S.

  • Covaryx
  • Covaryx HS
  • Essian
  • Estrace
  • Estratest
  • Femtrace
  • Gynodiol
  • Jatenzo
  • Menogen
  • Syntest D.S.
  • Syntest H.S.
  • Tlando

Available Dosage Forms:

  • Tablet

Uses for this Medicine

Androgens and estrogens are hormones. Estrogens are produced by the body in greater amounts in females. They are necessary for normal sexual development of the female and for regulation of the menstrual cycle during the childbearing years. Androgens are produced by the body in greater amounts in males. However, androgens are also present in females in small amounts.

The ovaries and adrenal glands begin to produce less of these hormones after menopause. This combination product is prescribed to make up for this lower production of hormones. This may relieve signs of menopause, such as hot flashes and unusual sweating, chills, faintness, or dizziness.

Androgens and estrogens may also be used for other conditions as determined by your doctor.

There is no medical evidence to support the belief that the use of estrogens (contained in this combination medicine) will keep the patient feeling young, keep the skin soft, or delay the appearance of wrinkles. Nor has it been proven that the use of estrogens during the menopause will relieve emotional and nervous symptoms, unless these symptoms are caused by other menopausal symptoms, such as hot flashes.

A paper called “Information for the Patient” should be given to you with your prescription. Read this carefully. Also, before you use an androgen and estrogen product, you and your doctor should discuss the good that it will do as well as the risks of using it.

This medicine is available only with your doctor's prescription.

Before using this Medicine

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Geriatric

This medicine has been tested and has not been shown to cause different side effects or problems in older women than it does in younger females.

Pregnancy

Estrogens (contained in this combination medicine) are not recommended for use during pregnancy, since some estrogens have been shown to cause serious birth defects in humans. Some daughters of women who took diethylstilbestrol (DES) during pregnancy have developed reproductive (genital) tract problems and, rarely, cancer of the vagina and/or uterine cervix when they reached childbearing age. Some sons of women who took DES during pregnancy have developed urinary-genital tract problems.

Androgens (contained in this combination medicine) should not be used during pregnancy because they may cause male-like changes in a female baby.

Breast Feeding

Use of this medicine is not recommended in nursing mothers. Estrogens pass into the breast milk and their possible effect on the baby is not known. It is not known if androgens pass into breast milk. However, androgens may cause unwanted effects in nursing babies such as too early sexual development in males or male-like changes in fema...