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Etelcalcetide Intravenous
  • Treatments
  • Hyperparathyroidism Secondary to Renal Impairment
  • Etelcalcetide (Intravenous)

Etelcalcetide (Intravenous)

Medically reviewed by Drugs.com. Last updated on Jun 5, 2022.

Commonly used brand name(s)

In the U.S.

  • Parsabiv

Available Dosage Forms:

  • Solution

Therapeutic Class: Endocrine-Metabolic Agent

Pharmacologic Class: Calcimimetic

Uses for etelcalcetide

Etelcalcetide injection is used to used to treat secondary hyperparathyroidism in patients with chronic kidney disease who are on dialysis. Hyperparathyroidism is a condition that is caused when the parathyroid glands located in the neck make too much parathyroid hormone (PTH). This hormone controls the concentrations of calcium and phosphorus in your blood. Paricalcitol helps lower the amount of PTH which lowers the calcium and phosphorus concentrations.

Etelcalcetide is to be given only by or under the direct supervision of your doctor.

Before using etelcalcetide

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For etelcalcetide, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to etelcalcetide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of etelcalcetide injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of etelcalcetide injection in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems

The presence of other medical problems may affect the use of etelcalcetide. Make sure you tell your doctor if you have any other medical problems, especially:

  • Bone disease or
  • Heart failure or
  • Seizures, or history of—Use with caution. May make these conditions worse.
  • Heart rhythm problem (eg, congenital long QT syndrome, QT prolongation), or history of or
  • Stomach or other digestive problems (eg, esophagitis, gastritis,...